The proceedings have been published in the Journal of Inherited Metabolic Disease     Volume 32 No 3 June 2009



First Annual Symposium on Pediatric Neurotransmitter
Diseases May 18 to 19, 2002 Annals of Neurology Vol 54 Supplement 6 2003 For a free copy of the Journal
[email protected]


2002 PND Medical Symposium
May 17th-19th


 First Annual Symposium on
 Pediatric Neurotransmitter Diseases
 Annals of Neurology
 Vol 54 Supplement 6 2003
For a free copy of the Journal email:
[email protected]

For session summaries click on the session titles

Session I- Neurochemistry Associated with Pediatric Neurotransmitter Diseases
Darryl C. De Vivo, MD- Chair

"Functional Aspects of GABA Neurotransmitter"
O.C. Snead, MD

"Biogenic Amines-Metabolism  and  Regulation"
Teodoro Bottliglieri, PhD

"GHB: A Potential Neurotransmitter in Mammalian CNS"
O.C Snead, MD

Session II- Clinical Overview of PNDs                                                  
Andrea Gropman-Chair
"Aromatic L-Amino Acid Decarboxylase Deficiency"
Kathryn Swoboda , MD

" Tyrosine Hydroxylase Deficiency"
Georg F. Hoffmann, MD

"Segawa Disease (Dominantly Inherited GTP I Cyclohydrolase Deficiency)"
Darryl C. De Vivo, MD

"Succinc Semialdehyde Dehydrogenase (SSADH) Deficiency (4 Hydroxybutyric Aciduria) in Children and Adults"
Phillip Pearl, MD

Session III- Diagnoses and Therapeutic Interventions for PND' s   
Keith Hyland, PhD- Chair

"The Clinicians's Approach to the Diagnosis of the Patient with a Suspected PND"
Georg F. Hoffmann, MD

"The Lumbar Puncture for Diagnosis of PNDs"
Keith Hyland , PhD

"Therapeutic Interventions for Disorders of Biogenic Amine Metabolism"
Blair Ford, MD

"Vigabatrin and Newer Interventions in SSADH Deficiency"
Andrea Gropman, MD

Summary Discussion -"Strategy Planning for Implementation of Goals and Objectives of the PND Association
Chaired by the Scientific Organization Committee and Invited Speakers 

Session IV- Animal Models of PND's  

Kathryn Swoboda, MD-Chair

"Animal Models of  Catecholamine Defects"
Marc Caron, MD

"New Therapeutic Insights form a Murine Model of SSADH Deficiency"
K. Michael Gibson, PhD

"The hph- mouse , A Model of GTP I Cyclohydrolase Deficiency"
Keith Hyland, PhD

Session V- Future Directions for Research and Treatment of PNDs
Georg Hoffmann, MD- Chair

"The Potential Role of Hepatocyte Repopulation in Treating PNDs"
Markus Grompe MD

"Genetic Modification of Human Neuronal Stem Cells"Implications for Brain Repair"
Clive Svendsen, PhD

Summary Discussion- "What are the Future Objectives of the PND Association and How Do We Coordinate to Achieve Our Goals"
Chaired by the Scientific Organizing Committee and Invited Speakers 

K. Michael Gibson, PhD - Symposium Summary