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PROGRAM SCHEDULE
For session summaries click on the session titles
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Friday,
May 17 2002
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3:00
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--
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7:00
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pm
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Arrival and Registration
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7:30
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--
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10:00
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pm
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Welcoming Reception (private invitation only)
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Saturday,
May 18th 2002
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7:00
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--
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8:30
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am
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Registration and Breakfast
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8:30
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--
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8:45
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am
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Giovanna Spinella, MD --
Welcome and Opening Remarks
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8:45
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--
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10:20
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am
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Session I � Neurochemistry Associated
with Pediatric Neurotransmitter Diseases
Darryl
C. De Vivo, MD -- Chair
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8:45
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--
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9:10
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am
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O.C. Snead, MD -- �Functional Aspects of GABA
Neurotransmission�
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9:10
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--
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9:40
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am
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Teodoro Bottiglieri, PhD -- �Biogenic
Amines-Metabolism and Regulation�
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9:40
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--
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10:05
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am
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O. C. Snead, MD -- �GHB: A Potential Neurotransmitter
in Mammalian CNS�
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10:05
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--
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10:20
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am
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Roundtable Discussion
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10:20
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--
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10:35
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am
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Coffee Break
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10:35
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--
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12:30
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pm
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Session II � Clinical Overview of PNDs
Andrea Gropman, MD -- Chair
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10:35
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--
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11:00
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am
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Kathryn Swoboda, MD -- �Aromatic L-Amino Acid
Decarboxylase Deficiency�
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11:00
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--
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11:25
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am
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George F. Hoffmann, MD -- �Tyrosine Hydroxylase
Deficiency�
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11:25
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--
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11:50
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pm
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Darryl C. De Vivo, MD -- �Segawa Disease (Dominantly
Inherited GTP Cyclohydrolase Deficiency)
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11:50
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--
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12:15
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pm
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Phillip Pearl, MD -- �Succinic Semialdehyde
Dehydrogenase (SSADH) Deficiency (4-Hydroxybutyric Aciduria) in Children
and Adults�
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12:15
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--
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12:30
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pm
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Roundtable Discussion
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12:30
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--
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1:30
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pm
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Lunch
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1:30
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--
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4:10
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pm
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Session III -- Diagnoses and Therapeutic Intervention for PNDs
Keith Hyland, PhD -- Chair
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1:30
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--
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2:00
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pm
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George F. Hoffmann, MD -- �The Clinician�s Approach
to the Diagnosis of the Patient with a Suspected PND�
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2:00
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--
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2:30
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pm
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Keith Hyland, PhD -- �The Lumbar Puncture for
Diagnosis of PNDs�
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2:30
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--
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2:45
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pm
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Roundtable Discussion
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2:45
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--
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3:00
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pm
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Coffee Break
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3:00
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--
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3:30
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pm
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Blair Ford, MD -- �Therapeutic Intervention for
Disorders of Biogenic Amine Metabolism�
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3:30
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--
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3:55
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pm
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Andrea Gropman, MD -- �Vigabatrin and Newer
Interventions in SSADH Deficiency�
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3:55
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--
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4:10
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pm
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Roundtable Discussion
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4:10
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--
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5:00
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pm
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Summary Discussion -- �Strategy Planning for
Implementation of Goals and Objectives of the PND
Association�-Chaired by the Scientific Organization Committee and
Invited Speakers (open to all participants)
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5:00
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pm
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Adjourn
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7:30
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pm
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Conference Dinner (private invitation only)
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Sunday, May 19, 2002
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7:00
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--
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8:00
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am
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Breakfast
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8:15
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--
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9:50
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am
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Session IV � Animal Models of PNDs
Kathryn Swoboda, MD -- Chair
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8:15
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--
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8:40
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am
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Marc Caron, MD -- �Animal Models of Catecholamine
Defects�
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8:40
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--
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9:10
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am
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K. Michael Gibson, PhD -- �New Therapeutic Insights
from a Murine Model of SSADH Deficiency�
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9:10
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--
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9:35
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am
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Keith Hyland, PhD -- �The hph-1 Mouse, a Model of GTP
Cyclohydrolase Deficiency�
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9:35
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--
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9:50
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am
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Roundtable Discussion
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9:50
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--
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10:05
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am
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Coffee Break
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10:05
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--
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11:15
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am
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Session V -- Future Directions for Research And Treatment of
PNDs
G. Hoffmann, MD -- Chair
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10:05
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--
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10:35
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am
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Markus Grompe, MD -- �The Potential Role of Hepatocyte
Repopulation in Treating PNDs�
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10:35
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--
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11:05
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am
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Clive Svendsen, PhD �
�Genetic Modification of Human Neuronal Stem Cells;
Implications for Brain Repair�
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11:05
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--
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11:15
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am
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Roundtable Discussion
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11:15
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12:10
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pm
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Summary Discussion -- �What are the Future Objectives
of the PND Association, and How Do We Coordinate to Achieve Our
Goals�-Chaired by the Scientific Organizing Committee and Invited
Speakers (open to all participants)
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12:10
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12:25
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pm
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Giovanna Spinella, MD and Darryl C. De Vivo, MD
--Concluding Remarks and Closing
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12:30
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pm
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Adjourn
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